Mesothelioma Palliative Care Guide

Palliative care improves quality of life for mesothelioma patients. Learn about symptom management, hospice eligibility, and support options.

Key Facts
Palliative care can be received alongside active cancer treatment
Early palliative care integration improves quality of life and may extend survival
Hospice is for life expectancy of 6 months or less; palliative care is available at any stage
Thoracentesis, pleurodesis, and indwelling catheters manage pleural effusions

Understanding Palliative Care

Palliative care focuses on relieving symptoms and improving quality of life, and can be provided alongside active treatments like chemotherapy, immunotherapy, or surgery.

Palliative Care ≠ Hospice

Palliative care is NOT the same as hospice care. You can receive palliative care while still pursuing curative treatment. It focuses on symptom relief and quality of life at any stage of illness.

Palliative Care vs. Hospice Care

AspectPalliative CareHospice Care
When startedAny time after diagnosisLife expectancy 6 months or less
Treatment goalSymptom relief + active treatmentComfort only, no curative treatment
SettingHospital, clinic, or homeUsually home or hospice facility
DurationThroughout illnessEnd of life

Both approaches prioritize comfort, dignity, and quality of life, but palliative care can accompany aggressive treatment.

Symptoms Addressed by Palliative Care

Respiratory Symptoms

Shortness of breath:

  • Often the most distressing symptom
  • Caused by tumor growth, pleural effusion, or reduced lung capacity
  • Managed with medications, oxygen, positioning techniques

Pleural effusions (fluid buildup):

  • Thoracentesis: Drains fluid for immediate relief
  • Pleurodesis: Seals pleural space to prevent reaccumulation
  • Indwelling catheter: Allows ongoing drainage at home

Pain Management

Mesothelioma pain is managed through multiple approaches:

  • Medications: From over-the-counter to prescription opioids
  • Nerve blocks: Targeted pain relief
  • Low-dose radiation: Can shrink tumors causing pain
  • Physical therapy: Maintain mobility and function

Other Symptoms

SymptomManagement Approaches
FatigueEnergy conservation, activity planning, nutrition support
NauseaAnti-nausea medications, dietary modifications
Appetite lossNutritional counseling, appetite stimulants
Anxiety/DepressionCounseling, medication, support groups
Sleep problemsSleep hygiene, medication when needed

The Palliative Care Team

A comprehensive palliative care team may include:

  • Palliative medicine physician: Leads care coordination
  • Nurse practitioners: Day-to-day symptom management
  • Social workers: Emotional support, practical assistance
  • Chaplains: Spiritual care
  • Pharmacists: Medication management
  • Physical/Occupational therapists: Maintain function
  • Dietitians: Nutritional support

When to Consider Palliative Care

Early Integration Is Best

Research shows patients who receive palliative care alongside standard treatment report better quality of life, have improved symptom control, experience less depression and anxiety, and may even have better survival outcomes.

  • Report better quality of life
  • Have improved symptom control
  • May even have better survival outcomes
  • Experience less depression and anxiety

Consider palliative care when:

  • You’re diagnosed with mesothelioma (at any stage)
  • Symptoms are affecting your quality of life
  • Treatment side effects are difficult to manage
  • You need help making treatment decisions
  • You want comprehensive support for you and your family

Hospice Care

Hospice is appropriate when:

  • Life expectancy is 6 months or less
  • Curative treatments have been stopped
  • The focus shifts to comfort and quality of remaining time

Hospice Eligibility Criteria

Patients typically qualify when experiencing:

  • Rapid physical decline
  • Severe symptoms reducing quality of life
  • Choice to focus on comfort over aggressive treatment
  • Disease progression despite treatment

Levels of Hospice Care

LevelDescription
Routine home careRegular visits from hospice team
Continuous home care24-hour care during crisis periods
Inpatient careShort-term facility care for symptom management
Respite careTemporary relief for caregivers

Hospice Services

For patients:

  • Symptom management and pain control
  • Emotional and spiritual support
  • Assistance with daily activities
  • 24/7 on-call nursing support
  • Medical equipment and supplies

For families:

  • Caregiver education and support
  • Respite care (breaks for caregivers)
  • Bereavement counseling
  • Support groups

Procedures for Symptom Relief

Thoracentesis

Purpose: Drain pleural fluid causing shortness of breath

Process:

  • Needle inserted through chest wall
  • Fluid drained (often 1-2 liters)
  • Outpatient procedure
  • May need to be repeated

Pleurodesis

Purpose: Prevent fluid reaccumulation

Process:

  • Talc or other agent inserted into pleural space
  • Creates adhesion between lung and chest wall
  • More permanent solution than thoracentesis
  • Can be done via VATS (video-assisted thoracic surgery)

Indwelling Pleural Catheter

Purpose: Allow ongoing fluid drainage at home

Process:

  • Small catheter placed in chest wall
  • Patient or caregiver drains fluid as needed
  • Avoids repeated hospital visits
  • Good option for recurrent effusions

Quality of Life Considerations

Physical Well-Being

  • Maintain activity as tolerated
  • Conserve energy for important activities
  • Accept help with tasks when needed
  • Focus on what you can do, not limitations

Emotional Health

  • Allow yourself to feel all emotions
  • Seek counseling or support groups
  • Stay connected with loved ones
  • Consider spiritual support

Practical Matters

  • Discuss advance directives
  • Communicate wishes to family
  • Address financial and legal concerns
  • Accept practical help from others

Caregiver Support

Caregivers also need care:

  • Respite services: Take breaks
  • Support groups: Connect with others in similar situations
  • Counseling: Process difficult emotions
  • Practical assistance: Help with tasks, transportation, meals
Can I receive palliative care while continuing treatment?

Yes. Unlike hospice, palliative care can be integrated with active cancer treatment—chemotherapy, immunotherapy, even surgery. It focuses on symptom management and quality of life at any stage.

What symptoms can palliative care help manage?

Palliative care addresses shortness of breath, pain, pleural effusions (fluid buildup), fatigue, nausea, anxiety, depression, and sleep problems. The team coordinates multiple approaches for each symptom.

What support is available for my family?

Palliative care includes caregiver support: education, respite services, counseling, and practical assistance. When transitioning to hospice, bereavement counseling continues for 13 months.

When should I consider hospice care?

Hospice is appropriate when life expectancy is 6 months or less and the focus shifts from curative treatment to comfort care. Your medical team can help determine when this transition is appropriate.

Finding Palliative Care

  • Your oncology team: Can refer you to palliative care
  • Hospital palliative care services: Most cancer centers have programs
  • Community hospice organizations: Many offer palliative care too
  • Palliative Care Provider Directory: getpalliativecare.org

References

New England Journal of Medicine. (2010). Early Palliative Care for Patients with Metastatic Non-Small-Cell Lung Cancer.
https://pubmed.ncbi.nlm.nih.gov/20818875/

Journal of Clinical Oncology. (2017). Integration of Palliative Care into Standard Oncology Care.
https://pubmed.ncbi.nlm.nih.gov/27069075/

Center to Advance Palliative Care. (2024). Get Palliative Care Provider Directory.
https://getpalliativecare.org/